Indicators

 

VPH-DARE@IT’s aim is to enable more objective, earlier, predictive and individualised diagnoses and prognoses of dementias to cope with the challenge of an ageing European society.

Currently doctors rely on basic cognitive tests and conventional brain scans to diagnose dementia, but these are not able to recognise the disease at an early stage. If a much wider range of markers can be identified which enable a better and earlier diagnosis, then doctors will have more time to delay the progression of the disease.

The expected impact of the project will influence the scientific, clinical and industrial communities across Europe and internationally to improve the healthcare of dementia patients. This would both improve patients’ quality of life, and also reduce the burden on carers and the costs of supporting people with dementia.

Measure of Success
Indicator of Impact
Target
Overall clinical impact
More objective, standardised differential assessment.
Time lapse between the onset of cognitive and memory deficits and its first diagnosis.
Enable earlier diagnosis by reducing the current 20-months time lapse from first admission to diagnosis.
Scientific impact – dementia model
Deliver a systematic, multifactorial and multiscale modelling approach to understanding dementia;Explore the lifestyle and environmental factors that predispose to its development
At least 2 clinical and 2 technical landmark publications describing the VPH-DARE@IT strategy for multiscale multifactorial and multi-paradigm dementia modelling and its application/impact in brain disease.
Industrial impact
Technology uptake in the form of modules or systems: no. of patents and licence agreements.
At least one success story in the form of tech transfer agreements and patents available at the end of the project.
Fast concept-prototype-product cycle thanks to VPH development frameworks.
Dissemination impact
Dissemination to and engagement with the wider community.
Presence on the internet, existence of newsletters, production of a video for the general public, participation in wider dissemination events.
Training impact
Contribution to and organisation of training events.
At least yearly training events in three areas: software platforms (Developer / User Workshops), clinical uptake (e.g. Clinical Training Courses), general scientific dissemination (EIBIR Summer School).
Infrastructural impact
Open source platform for VPH modelling and image-based biomarker extraction in dementia available for the VPH community.
GIMIAS and Nifty well-documented & supported, integrated in VPH Toolkit, widely used in the community.
VPH-share infostructure demonstrates scalability and reusability with large databases in VPH-DARE@IT

 

Return on investment: The project will reduce the costs of supporting people with dementia.